973 research outputs found

    Evaluating the productive efficiency and performance of U.S. commercial banks

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    This paper reviews various approaches to the measurement of core inflation that have been proposed in recent years. The objective is to determine whether the European Central Bank (ECB) should pay special attention to one or other of these measures in assessing inflation developments in the euro area. I put particular emphasis on the conceptual and practical problems that arise in the measurement of core inflation, and propose some criteria that could be used by the ECB to choose a core inflation measure.Banks and banking

    Significant morphological change in osteoarthritic hips identified over 6-12 months using Statistical Shape Modelling

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    Acknowledgements We are grateful to all the study participants. We thank Lana Gibson and Jennifer Scott for their expertise with the iDXA scanner as well as iDXA precision data. Funding source This study was supported by an award (Ref: WHMSB_AU068/071) from the Translational Medicine Research Collaboration – a consortium made up of the Universities of Aberdeen, Dundee, Edinburgh and Glasgow, the four associated NHS Health Boards (Grampian, Tayside, Lothian and Greater Glasgow & Clyde), Scottish Enterprise and initially Wyeth, now Pfizer. The funder had no involvement in the collection, analysis and interpretation of data; in the writing of the manuscript; or in the decision to submit the manuscript for publication. Dr J.S. Gregory was the holder of an MRC New Investigator award (Ref: G0901242).Peer reviewedPostprin

    Reproducibility and Diagnostic Accuracy of Kellgren-Lawrence Grading for Osteoarthritis Using Radiographs and Dual-Energy X-ray Absorptiometry Images

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    Copyright © 2014 The International Society for Clinical Densitometry. Published by Elsevier Inc. All rights reserved. The authors would like to thank all the study volunteers, radiographers Lana Gibson and Jennifer Scott as well as Carol McKerron for administrative support. The acquisition of scans was supported in part by an award (Ref: WHMSB_AU_068_071) from the Translational Medicine Research Initiative - a consortium made up of the Universities of Aberdeen, Dundee, Edinburgh and Glasgow, the four associated NHS Health Boards (Grampian, Tayside, Lothian and Greater Glasgow & Clyde), Scottish Enterprise and Pfizer. Kanako Yoshida is funded by the Grampian Osteoporosis Trust (GOT). Jennifer Gregory is supported by the Medical Research Council [G0901242].Peer reviewedPostprin

    Prenatal Exposure to Organophosphates, Paraoxonase 1, and Cognitive Development in Childhood

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    Background: Prenatal exposure to organophosphate pesticides has been shown to negatively affect child neurobehavioral development. Paraoxonase 1 (PON1) is a key enzyme in the metabolism of organophosphates

    Lessons Learned for the Assessment of Children’s Pesticide Exposure: Critical Sampling and Analytical Issues for Future Studies

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    In this article we examine sampling strategies and analytical methods used in a series of recent studies of children’s exposure to pesticides that may prove useful in the design and implementation of the National Children’s Study. We focus primarily on the experiences of four of the National Institute of Environmental Health Sciences/U.S. Environmental Protection Agency/ Children’s Centers and include University of Washington studies that predated these centers. These studies have measured maternal exposures, perinatal exposures, infant and toddler exposures, and exposure among young children through biologic monitoring, personal sampling, and environmental monitoring. Biologic monitoring appears to be the best available method for assessment of children’s exposure to pesticides, with some limitations. It is likely that a combination of biomarkers, environmental measurements, and questionnaires will be needed after careful consideration of the specific hypotheses posed by investigators and the limitations of each exposure metric. The value of environmental measurements, such as surface and toy wipes and indoor air or house dust samples, deserves further investigation. Emphasis on personal rather than environmental sampling in conjunction with urine or blood sampling is likely to be most effective at classifying exposure. For infants and young children, ease of urine collection (possible for extended periods of time) may make these samples the best available approach to capturing exposure variability of nonpersistent pesticides; additional validation studies are needed. Saliva measurements of pesticides, if feasible, would overcome the limitations of urinary metabolite-based exposure analysis. Global positioning system technology appears promising in the delineation of children’s time–location patterns

    Polarization and relaxation of radon

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    Investigations of the polarization and relaxation of 209^{209}Rn by spin exchange with laser optically pumped rubidium are reported. On the order of one million atoms per shot were collected in coated and uncoated glass cells. Gamma-ray anisotropies were measured as a signal of the alignment (second order moment of the polarization) resulting from the combination of polarization and quadrupole relaxation at the cell walls. The temperature dependence over the range 130^\circC to 220^\circC shows the anisotropies increasing with increasing temperature as the ratio of the spin exchange polarization rate to the wall relaxation rate increases faster than the rubidium polarization decreases. Polarization relaxation rates for coated and uncoated cells are presented. In addition, improved limits on the multipole mixing ratios of some of the main gamma-ray transitions have been extracted. These results are promising for electric dipole moment measurements of octupole-deformed 223^{223}Rn and other isotopes, provided sufficient quantities of the rare isotopes can be produced.Comment: 4 pages, 4 figure

    Tunable-filter imaging of quasar fields at z~1. I. A cluster around MRC B0450-221

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    Using a combination of multicolour broad- and narrow-band imaging techniques and follow-up spectroscopy, we have detected an overdensity of galaxies in the field of quasar MRC B0450-221, whose properties are consistent with a cluster at the quasar redshift z=0.9. An excess of red galaxies (V-I>2.2, I-K'>3.8) is evident within 1' of the quasar, with the colours expected for galaxies at z=0.9 that have evolved passively for 3 Gyr or more. A number of line-emitting galaxies (nine candidates with equivalent widths EW>70A) are also detected in the field using the TAURUS Tunable Filter (TTF). Three have been confirmed spectroscopically to indeed lie at z=0.9. The TTF candidates with the strongest [O II] line emission cluster in a group which lies 200-700 kpc away from the quasar and the red galaxy excess, and therefore most likely on the outskirts of the cluster. These observations are the first in a series probing quasar environments at z~1 with TTF.Comment: Accepted for publication in AJ. 25 pages, 24 figs (large files in jpg or gif format), uses emulateapj.st

    Investigation of the Relationship Between Susceptibility Loci for Hip Osteoarthritis and Dual X-Ray Absorptiometry–Derived Hip Shape in a Population-Based Cohort of Perimenopausal Women

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    This publication is the work of the authors and does not necessarily reflect the views of any funders. Supported by the UK Medical Research Council (grant G1001357 for collection of hip shape), and the Wellcome Trust (grants WT092830M for collection of hip shape and WT088806 for genotyping). Core support for the Avon Longitudinal Study of Parents and Children is provided by the UK Medical Research Council, the Wellcome Trust (102215/2/13/2), and the University of Bristol. Dr. Baird's work was supported by Arthritis Research UK (grant 20244). Mr. Faber's work was supported by an Elizabeth Blackwell Institute Clinical Research Primer Scheme.Peer reviewedPostprin
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